Cuneiform (from the Latin word for "wedge-shaped") can refer to:

• Cuneiform script, an ancient writing system originating in Mesopotamia in the 4th millennium BC
• Cuneiform (anatomy), three bones in the human foot
• Cuneiform cartilages
• Cuneiform Records, a music record label
• CuneiForm (software), an optical character recognition tool
• Cuneiform (Unicode block)

Cuneiform script is one of the earliest systems of writing, distinguished by its wedge-shaped marks on clay tablets, made by means of a blunt reed for a stylus. The name cuneiform itself simply means "wedge shaped", from the Latin cuneus "wedge" and forma "shape," and came into English usage probably from Old French cunéiforme.