The Grand River is a tributary of Lake Erie, 102.7 miles (165.3 km) long, in northeastern Ohio in the United States. Via Lake Erie, the Niagara River and Lake Ontario, it is part of the watershed of the St. Lawrence River, which flows to the Atlantic Ocean. It drains an area of 712 mi² (1844 km²).

Grand River is a village in Lake County, Ohio, United States, along the Grand River. The population was 399 at the 2010 census.