Early modern Europe is the period in the history of Europe which spanned the centuries between the end of the Middle Ages and the beginning of the Industrial Revolution, roughly the late 15th century to the late 18th century. The early modern period is often considered to have begun with such events as the beginning of the High Renaissance in Italy; the invention of moveable type printing in the 1450s; the Fall of Constantinople in 1453; the end of the Wars of the Roses in 1485; the Voyages of Christopher Columbus and the completion of the Reconquista in 1492 or the start of the Protestant Reformation in 1517. Its end point is often linked with the outset of the French Revolution in 1789, or with the more nebulous origins of industrialism in late 18th century Britain. As with most periodizations of history, however, the precise dates chosen vary.