The Cappadocian Fathers are Basil the Great (330–379), who was bishop of Caesarea; Basil's younger brother Gregory of Nyssa (c.332–395), who was bishop of Nyssa; and a close friend, Gregory of Nazianzus (329–389), who became Patriarch of Constantinople. The Cappadocia region, in modern-day Turkey, was an early site of Christian activity, with several missions by Paul in this region.