The term SPACE (capitalized) can refer to:

• SPACE, a Canadian science-fiction channel
• DSPACE, a term in computational complexity theory
• Small Press and Alternative Comics Expo, an annual comic book convention
• Society for Promotion of Alternative Computing and Employment, located in Trivandrum, Kerala, India
• Spectroscopic All Sky Cosmic Explorer, a proposed satellite designed to measure the baryon acoustic oscillations

Space is the boundless three-dimensional extent in which objects and events have relative position and direction. Physical space is often conceived in three linear dimensions, although modern physicists usually consider it, with time, to be part of a boundless four-dimensional continuum known as spacetime. The concept of space is considered to be of fundamental importance to an understanding of the physical universe. However, disagreement continues between philosophers over whether it is itself an entity, a relationship between entities, or part of a conceptual framework.