An organophosphate (sometimes abbreviated OP) or phosphate ester is the general name for esters of phosphoric acid. Many of the most important biochemicals are organophosphates, including DNA and RNA, as well as many of the cofactors essential for life. Organophosphates are the basis of many insecticides, herbicides, and nerve agents. The United States Environmental Protection Agency lists organophosphates as very highly acutely toxic to bees, wildlife, and humans. Recent studies suggest a possible link to adverse effects in the neurobehavioral development of fetuses and children, even at very low levels of exposure. Organophosphates are widely used as solvents, plasticizers, and EP additives.