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Opioid modulator
An
opioid modulator
(or
opioid receptor modulator
) is a
drug
which has mixed
agonist
and
antagonist
actions at different
opioid receptors
and thus cannot clearly be described as either an opioid
agonist
or
antagonist
. An example of an opioid modulator is
buprenorphine
, which is a
partial agonist
of the
μ-opioid receptor
and an antagonist of the
κ-opioid receptor
.
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