Intramuscular fat (or Intramuscular triglycerides [IMTG]) is located throughout skeletal muscle. It is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat has been associated with conditions such as insulin resistance and type 2 diabetes. The human immunodeficiency virus (HIV)-lipodystrophy syndrome is associated with over-accumulation of intramuscular fat, which may contribute to AIDS wasting syndrome.