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Ganglioside
A
ganglioside
is a molecule composed of a
glycosphingolipid
(
ceramide
and
oligosaccharide
) with one or more
sialic acids
(e.g.
n-acetylneuraminic acid
, NANA) linked on the
sugar chain
. NeuNAc, an acetylated derivative of the carbohydrate sialic acid, makes the head groups of gangliosides anionic at
pH
7, which distinguishes them from
globosides
.
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