Carbon monoxide-releasing molecules (CO-RMs) are chemical compounds that release controlled amounts of carbon monoxide (CO) to cells and tissues and are being developed as potential therapeutic agents. Although long recognized as a poison, CO also exhibits beneficial effects in small doses. These effects include anti-inflammatory activity, vasodilatation, and cardioprotection. CO is produced in mammals during the degradation of heme by heme oxygenase-1, a redox-sensitive enzyme induced by oxidative stress. It is this enzymatic reaction that inspired the development of synthetic CO-RMs.

A corm, bulbo-tuber, or bulbotuber is a short, vertical, swollen underground plant stem that serves as a storage organ used by some plants to survive winter or other adverse conditions such as summer drought and heat (estivation).