Amyloidosis is a rare disease that results from the buildup of misfolded proteins known as
amyloids. When proteins that are normally
dissolvable in water fold to become amyloids, they become insoluble and deposit in
organs or
tissues, disrupting normal function. The type of protein that is misfolded and the organ or tissue in which the misfolded proteins are deposited determine the clinical manifestations of amyloidosis.