The Zuni (Zuñi) River is a tributary of the Little Colorado River in the southwestern United States. It has its origin in Cibola County, New Mexico, in the Zuñi Mountains at the Continental Divide. The river flows off the western slopes of the Zuñi Mountains in a generally southwesterly direction through the Zuni Indian Reservation to join the Little Colorado River in eastern Arizona. The Zuni River is approximately long, and has a drainage basin in New Mexico of approximately .