Wazir Akbar Khan (1816–1845; ), born as Mohammad Akbar Khan and also known as Amir Akbar Khan , was an Afghan prince, general, and finally emir for about three years until his death. His fame began with the 1837 Battle of Jamrud, while attempting to regain Afghanistan's second capital Peshawar from the Sikh army of British Punjab.

Wazir Akbar Khan is a neighbourhood in northern Kabul, Afghanistan, named after the 19th century Afghan Emir Wazir Akbar Khan. It is one of the wealthiest parts in Kabul. Many foreign embassies are located there, including the American and Canadian. The Kabul International Airport is also located in the Wazir Akbar Khan neighborhood.