The Odd Couple is a play by Neil Simon. Following its premiere on Broadway in 1965, the characters were revived in a successful 1968 film and 1970s television series, as well as other derivative works and spin-offs. The plot concerns two mismatched roommates: the neat, uptight Felix Ungar and the slovenly, easygoing Oscar Madison. Simon adapted the play in 1985 to feature a pair of female roommates (Florence Ungar and Olive Madison) in The Female Odd Couple. An updated version of the 1965 show appeared in 2002 with the title Oscar and Felix: A New Look at the Odd Couple.

Odd Couple may refer to:

• The Odd Couple, a 1965 stage play by Neil Simon
  • The Odd Couple (film), a 1968 film based on the play
    • The Odd Couple (TV series), a 1970–1975 television show based on the film
      • The Oddball Couple, a 1975-1977 animated TV series
      • The New Odd Couple, a 1982-1983 sitcom remake
      • The Odd Couple (2015 TV series), a 2015 remake
    • The Odd Couple II, 1998 sequel to the 1968 film
  • The Female Odd Couple, a version adapted by Simon in 1985 with the gender roles reversed
• Odd Couple (film), (搏命單刀奪命搶) a 1979 kung fu movie
• The Odd Couple (album), a music recording by Gnarls Barkley
• Odd Couples, episode of The Suite Life of Zack & Cody
• Odd Couple, episode of The Fairly OddParents