This article is about the 2004 remake. For the original, see The Ladykillers.

The Ladykillers is a 2004 American black comedy thriller film directed by Joel and Ethan Coen. The Coens' screenplay was based on the 1955 British Ealing comedy film of the same name written by William Rose. The remake was produced by the Coens, Tom Jacobson, Barry Sonnenfeld and Barry Josephson. It stars Tom Hanks, Irma P. Hall, Marlon Wayans, J. K. Simmons, Tzi Ma and Ryan Hurst. It is the first time the Coens have worked with Tom Hanks as well as the film being their first remake. This was the first film in which Joel and Ethan Coen share both producing and directing credits; previously Joel had always been credited as director and Ethan as producer.