The T-80 is a third-generation main battle tank (MBT) designed and manufactured in the Soviet Union. A development of the T-64, it entered service in 1976. The T-80U was last produced in a factory in Omsk, Russia, while the T-80UD and further-developed T-84 continue to be produced in Ukraine. The T-80 and its variants are in service in Belarus, Cyprus, Kazakhstan, Pakistan, Russia, South Korea, and Ukraine. The chief designer of the T-80 was the Russian engineer Nikolay Popov.

T80 or T-80 may refer to:

• T-80 tank, a Soviet Union main battle tank
• Canon T80, a 1985 35mm SLR camera
• Pir Panjal Railway Tunnel, also known as T-80.
• Mercedes-Benz T80, a vehicle designed to break the world land speed record
• Route T80, a T-Way bus service operated by Transit Systems Sydney