The St. Joseph Metropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of four counties - three in northwest Missouri (Andrew, Buchanan, and DeKalb) and one in northeast Kansas (Doniphan) - anchored by the city of St. Joseph, comprising a total area of 1,673.93 square miles. As of the 2010 census, the MSA had a population of 127,329.