The Spanish missions in California comprise a series of 21 religious outposts; established by Catholic priests of the Franciscan order between 1769 and 1833, to expand Christianity among the Native Americans northwards into what is today the U.S. state of California. The missions were part of a major effort by the Spanish Empire to extend colonization into the most northern and western parts of Spain's North American claims. The missionaries introduced European fruits, vegetables, cattle, horses, ranching and technology into the region that became the New Spain province of Alta California; however, the missions also brought serious negative consequences to the Native American populations with whom the missionaries and other Spaniards came in contact.