South Central Pennsylvania is a region of the U.S. state of Pennsylvania that includes the fourteen counties of Adams, Cumberland, Dauphin, Franklin, Huntingdon, Juniata, Lancaster, Lebanon, Mifflin, Perry, Snyder, and York. Portions of western Schuylkill and Northumberland counties are also located in South Central Pennsylvania. Despite the designation "South Central Pennsylvania," many of the counties are geographically located in the southeastern portion of the state. Lancaster is the largest city in the region. Harrisburg, with a population of 49,528, is the second largest city in the region with a metropolitan area of 643,820 people, and is the capital of Pennsylvania.  York is the other significant city in the region. The Harrisburg-Lancaster-York television market (which formally includes Adams, Cumberland, Dauphin, Franklin, Juniata, Lancaster, Lebanon, Mifflin, Perry, and York counties) is the 39th largest market in the United States.