Zoe Palaiologina , who later changed her name to Sophia Palaiologina (; ca. 1440/49 – 7 April 1503), was a Byzantine princess member of the Imperial Palaiologos family, by marriage Grand Princess of Moscow as the second wife of Grand Prince Ivan III. Through her eldest son Vasili III, she was also the grandmother of Ivan the Terrible, the first  Tsar of All the Russias.