Soledad de Graciano Sánchez is the second-largest city of the state of San Luis Potosí in Mexico. It lies adjacent to the east side of the state's capital city of San Luis Potosí in the west-central part of the state. The city is the municipal seat of the municipality of the same name. The city had a 2005 census population of 215,968, while the municipality's population was 226,803. The municipality has an area of 280.95 km² (108.475 sq mi).