The Commune of Santiago is the central commune of the Santiago Province, located at the center of the Santiago Metropolitan Region in Chile's Central Zone. Locally, Santiago is usually abbreviated Stgo. It is also called as "Santiago Centro" (Downtown Santiago) in order to differentiate it from Greater Santiago, a larger entity which includes Santiago Commune along with other 36 communes.

Santiago Municipality may refer to:

• Santiago, Norte de Santander, Colombia
• Santiago, Rio Grande do Sul, Brazil
• Santiago, Agusan del Norte, Philippines
• Santiago, Ilocos Sur, Philippines