Río Grande is a city in Argentina, on the north coast of the eastern part of the Isla Grande de Tierra del Fuego. It has a population of 67,038, and is the industrial capital of the Tierra del Fuego Province.

The Río Grande (Spanish for "great river") is a river located on the island of Tierra del Fuego. It arises in the Chilean (western) part of the island and flows in a generally eastward direction, through the Argentine part and into the Argentine Sea. At its mouth lies the city of Río Grande, Argentina.