Poekilopleuron (meaning "varied ribs") is an extinct genus of megalosauroid tetanuran theropod dinosaur, which lived during the middle Bathonian of the Jurassic, about 168 to 165 million years ago. The genus has been used under many different spelling variants, although only one, Poekilopleuron, is valid. The type species is P. bucklandii, named after William Buckland, and many junior synonyms of it have also been erected. Few material is currently known, as the holotype was destroyed in World War II, although many casts of the material still exist.