Peno is an urban-type settlement and the administrative center of Penovsky District of Tver Oblast, Russia. It is located between Lake Peno and Lake Volgo, both located in the course of the Volga River and belonging to Upper Volga Reservoir. Population:

Peno was founded in the 1900s as a settlement to serve the railway station. It was located in Ostashkovsky Uyezd of Tver Governorate. From 1924, the settlement of Peno was made a center of a volost. In 1926, Peno was granted urban-type settlement status.