Nyuksensky District is an administrative and municipal district (raion), one of the twenty-six in Vologda Oblast, Russia. It is located in the northeast of the oblast and borders with Ustyansky District of Arkhangelsk Oblast in the north, Velikoustyugsky District in the east, Kichmengsko-Gorodetsky District in the southeast, Babushkinsky District in the south, Totemsky District in the southwest, and with Tarnogsky District in the west. The area of the district is . Its administrative center is the rural locality (a selo) of Nyuksenitsa. District's population: 11,714 (2002 Census); The population of Nyuksenitsa accounts for 43.7% of the district's total population.