Nové Zámky District (okres Nové Zámky) is a district in the Nitra Region of western Slovakia. Until 1918, the area of the district was split between several county of Kingdom of Hungary: the largest area in the north formed part of Nitra; an area in the south between Dvory nad Žitavou and Strekov  formed part of Komárno; an area in the north-east around Velké Lovce  formed part of Tekov; a sizable area in the east formed part of Esztergom (Ostrihom); and a small area around Salka formed part of Hont County.