Route 28 is a nominally south–north route and highway in the U.S. state of Massachusetts, running from the town of Eastham via Boston to the New Hampshire state line in Methuen. Following the route from its nominally southern end, Route 28 initially heads south to the town of Chatham then turns west to follow along the south shore of Cape Cod. In Falmouth, Route 28 turns north and continues through the western reaches of Plymouth and Norfolk counties, and travels for a while through Route 25. It then cuts through downtown Boston before heading north via Lawrence to the New Hampshire state line, where it continues as New Hampshire Route 28. Coincidentally, Route 28 travels through 28 municipalities.