Vin Mariani (French: Mariani wine) was a tonic and patent medicine created about 1863 by Angelo Mariani, a French chemist who became intrigued with coca and its economic potential after reading Paolo Mantegazza’s paper on coca's effects. In 1863, Mariani started marketing a wine called Vin Tonique Mariani (à la Coca du Pérou) which was made from Bordeaux wine and coca leaves.