Mamfe (also spelled Mamfé) is a city and capital of the Manyu A Division of the Southwest Region in Cameroon. It is located from the border of Nigeria, on the Manyu River. It has a population of 20,300 (2001 estimate). It is known as a centre for traditional religion and traditional medicine. It used to be known for bad infrastructure within the city limits, especially the roads, but in recent times the roads have been tarred and are currently in good condition. The roads leading in and out, however, remain untarred and are difficult to impassable during the rainy season.