Khanate of Bukhara (or Khanate of Bukhoro) (; ) was a Central Asian state from the second quarter of 16th century to the late 18th century. Bukhara became the capital of the short-lived Shaybanid empire during the reign of Ubaydallah Khan (1533–1540). The khanate reached its greatest extent and influence under its penultimate Shaybanid ruler, Abdullah Khan II (r. 1577–1598).