The Kanektok River is a stream in southwestern Alaska in the United States. Beginning in the Ahklun Mountains at Kagati and Pegati lakes, it flows westward into Kuskokwim Bay on the Bering Sea at the city of Quinhagak. Almost all of the river's course lies within the Togiak National Wildlife Refuge. The Quinhagak Village Corporation owns the land bordering the lowermost of the river.