IFE or Ife may refer to:

• Ife, an ancient Yoruba city in Ogun State of Nigeria
• Ifè language, a language spoken in Togo and Benin
• IFE Worldwide, food-and-drinks industry trade show events
• Federal Electoral Institute (Instituto Federal Electoral), organization that was responsible for organizing federal elections in Mexico
• Interactive Fiction Engine, software created by Simutronics
• In-flight entertainment, entertainment offered aboard airlines
• Institution of Fire Engineers, a worldwide body that provides research, training, conferences and professional qualifications for those interested in the science of fire fighting and science
• Instituto de Ferrocarriles del Estado, the Venezuelan institution for railways
• Institute of finance and economics of Mongolia, a business school in Mongolia
• International Friendship Exhibition, a museum in North Korea that holds gifts to Kim Il-sung and Kim Jong-il
• Islamic Forum Europe, a Muslim organization based in the United Kingdom, formed in 1978 by British Bangladeshi Muslims
• Institute for Energy Technology, the Norwegian Institute for Energy Technology

Ife (, also Ilé-Ifẹ̀) is an ancient Yoruba city in southwestern Nigeria. The city is located in the present day Osun State. Ife is about northeast of Lagos.