This article is about a geographic region in the United States. For the High Plains of Australia, see High Plains (Australia).

The High Plains are a subregion of the Great Plains mostly in the Western United States, but also partly in the Midwest states of Nebraska, Kansas, and South Dakota, generally encompassing the western part of the Great Plains before the region reaches the Rocky Mountains. The High Plains are located in southeastern Wyoming, southwestern South Dakota, western Nebraska, eastern Colorado, western Kansas, eastern New Mexico, western Oklahoma, and south of the Texas Panhandle. The southern region of the Western High Plains ecology region contains the geological formation known as Llano Estacado which can be seen from a short distance or from miles away on satellite maps. From east to west, the High Plains rise in elevation from around to over .