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Fulvestrant
Fulvestrant
(trade name
Faslodex
, by
AstraZeneca
) is a
drug
treatment of hormone receptor-positive metastatic
breast cancer
in
postmenopausal
women with disease progression following anti-estrogen therapy. It is a complete
estrogen receptor
antagonist
with no agonist effects, which in addition, accelerates the
proteasomal
degradation of the estrogen receptor. The drug has poor oral
bioavailability
, and is administered monthly via
intramuscular injection
.
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