As defined by the U.S. Office of Management and Budget and used by the U.S. Census Bureau for statistical purposes only, the Florence Metropolitan Statistical Area, is an area consisting of two counties in the Pee Dee region of northeastern South Carolina, anchored by the city of Florence. As of the 2000 census, the MSA had a population of 193,155 (though a July 1, 2009 estimate placed the population at 200,653).