Fabry disease (also known as
Fabry's disease,
Anderson-Fabry disease,
angiokeratoma corporis diffusum, and
alpha-galactosidase A deficiency) is a rare genetic
lysosomal storage disease, inherited in an
X-linked manner. Fabry disease can cause a wide range of systemic symptoms. It is a form of
sphingolipidosis, as it involves dysfunctional metabolism of
sphingolipids. The disease is named after one of its discoverers, Johannes Fabry (June 1, 1860 – June 29, 1930).