Emilio Largo is a fictional character and the main antagonist from the 1961 James Bond novel Thunderball. He appears in the 1965 film adaptation, again as the main antagonist, with Italian actor Adolfo Celi filling the role. Largo is also the main antagonist in the 1983 unofficial James Bond movie Never Say Never Again, a remake of Thunderball. In Never Say Never Again, the character's name, however, was changed to Maximillian Largo and he was portrayed by the Austrian actor Klaus Maria Brandauer.

The James Bond novels and film series feature a number of villainous characters who serve as primary antagonists. Each story normally features a main villain bent on world domination or destruction who seeks to defeat or kill Bond, often with the assistance of secondary characters. Bond typically confronts the villain during the story's climax and exposes the evil plot.