The Cauca River is a river in Colombia that lies between the Occidental and Central cordilleras. From its headwaters in southwestern Colombia near the city of Popayán, it joins the Magdalena River near Magangué in Bolívar Department, and the combined river eventually flows out into the Caribbean Sea. It has a length of to its junction with the Magdalena, for a total length of . from origin to seamouth. The river is under the supervision of the Corporación Regional del Cauca and the Corporación Autonoma Regional del Valle del Cauca, and is navigable for above its junction with the Magdalena.