Cagayan Valley (Filipino: Lambak ng Cagayan, Ibanag: Tana' nak Cagayan, Ilokano: Tanap ti Cagayan, Itawis: Tanap yo Cagayan, Malaueg: Ga-dang yo Cagayan) (designated as Region II or Region 02) is an administrative region in the Philippines located in the northeastern portion of Luzon. It is composed of five provinces: Batanes, Cagayan, Isabela, Nueva Vizcaya, and Quirino. The region has four cities: industrial center Cauayan, its regional center Tuguegarao, its primary growth center and investment hub Ilagan and its premier city Santiago.