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CD4
In
molecular biology
,
CD4
(
cluster of differentiation
4) is a
glycoprotein
found on the surface of immune cells such as
T helper cells
,
monocytes
,
macrophages
, and
dendritic cells
. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4
monoclonal antibody
that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the
CD4
gene
.
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