"Brian Song" is the title song from the 1979 film Monty Python's Life of Brian. The song which charts the growth of the Brian character to manhood was composed by Andre Jacquemin and Dave Howman with lyrics by Michael Palin. It was performed by sixteen-year-old Sonia Jones with a string and brass accompaniment in the style of a John Barry film theme (the entire brass section was performed via extensive multitracking by John Du Prez). It is included on the Monty Python's Life of Brian Album and on the CD Monty Python Sings. Martin Chilton the Culture Editor for The Telegraph website listed it as one of the five best Monty Python songs in 2013.

Brian's Song is a 1971 ABC Movie of the Week that recounts the details of the life of Brian Piccolo (played by James Caan), a Wake Forest University football player stricken with terminal cancer after turning pro, told through his friendship with Chicago Bears running back teammate and Pro Football Hall of Famer Gale Sayers (Billy Dee Williams), who helps him through the difficult struggle. The production was such a success on ABC that it was later shown in theaters by Columbia Pictures with a major premiere in Chicago; however, it was soon withdrawn due to a lack of business. Critics have called the movie one of the finest telefilms ever made. A 2005 readers poll taken by Entertainment Weekly ranked 'Brian's Song' seventh in its list of the top "guy-cry" films ever made.