Bethlehem is a city in Lehigh and Northampton counties in the Lehigh Valley region of the eastern portion of the U.S. state of Pennsylvania. As of the 2010 census, the city had a total population of 74,982, making it the seventh largest city in Pennsylvania, after Philadelphia, Pittsburgh, Allentown, Erie, Reading, and Scranton. Of this, 55,639 were in Northampton County, and 19,343 were in Lehigh County.